A new marker of blood clotting in heart disease
Formation of blood clots in heart blood vessels contribute to heart disease and trigger heart attacks. The goal of this research is to understand why this happens.
Advanced manufacturing of new vascular grafts
Building next generation vascular grafts with highly controlled architecture that would be effective as off-the-shelf materials for bypass surgery.
Advancing dietary advice to lower blood pressure
Advancing dietary advice to lower blood pressure
Advancing vascular graft development in NSW
Integrating transgenic tools and high-resolution spatial gene mapping to study the effects of comorbidities on vascular graft failure.
Artificial muscles for ventricular assist devices
A new muscle-inspired cardiac assist device to fill the gap in donor hearts.
Exploring Thrombotic Risk Factors at the Molecular Level
Quantitative Imaging At Nanoscale with SUper-resolution (QIAN SU) for Probing, Diagnosing and Monitoring Thrombotic Disease at the Molecular Level.
How diabetes and kidney disease affect heart health
Understanding how matrix protein signalling in diabetes and kidney disease affect development of cardiovascular disease.
Hyperacute cardiac computed tomography in stroke diagnosis and prevention
A new muscle-inspired cardiac assist device to fill the gap in donor hearts.
Implementing exercise for congenital heart disease
Implementing a telehealth model of care to improve access to exercise and lifestyle services for young people with congenital heart disease.
Improving cardiometabolic health for people with HIV
Understanding the impact of a new cardiometabolic medication on cardiovascular risk in people with HIV at elevated metabolic risk.
Improving kidney disease outcomes in heart failure
This project will establish an international consortium to identify the best way to assess kidney disease progression in heart failure trials.
Nanotechnology for longer lasting valve replacements
Integration of drug elution technology to improve the biological resilience of transcatheter heart valve leaflet replacements.
Novel and Safe Anticoagulants for Stroke
Development of novel clot busting drugs and anti-clotting stents for the safe and effective treatment of acute ischaemic stroke.
Reducing toxic lipids for better cardiovascular health
Targeting lipid synthesis or lipid oxidation to reduce accumulation of toxic lipids that drive cardiovascular complications in obesity and diabetes.
Robotic tool to early detect risk of cardiac device
Develop new pre-procedural planning soft robotic tool capable of accurately predicting complication risks in patients with cardiac devices upfront.
Building next generation vascular grafts with highly controlled architecture that would be effective as off-the-shelf materials for bypass surgery.
Enhancing engraftment of stem cell derived heart muscle
To use tropoelastin and platelet-derived growth factor to produce a second-generation stem-cell derived cardiomyocytes product with enhanced engraftment and function for the treatment of heart failure.
Restoring energy generation in heart failure
Fixing failing hearts by repairing the connection between energy-generation and mechanical function.
Manufacturing artificial heart muscles
Muscle-inspired cardiac assist device addressing the donor heart shortage and improving end-stage heart failure treatment.
Blood pressure lowering in intracerebral haemorrhage
Using a blood biomarker for early identification of a stroke caused by intracerebral haemorrhage.
Oxygen-sensitive systems for delivering therapeutic proteins to human heart cells
Develop a delivery system to repair damaged heart muscle to improve patient health outcomes after a heart attack.