Ultrasound technology to move fluids within the body
A breakthrough dialysis machine that can be used at home or by rural health workers in remote settings
Novel medical treatment technology that incorporates 3D printing for corneal diseases and injuries
Developing hardware for gene delivery
Customised total knee replacement technology platform
Platform technology to repair bone, cartilage and connective tissues
Validating the safety of Platelet Derived Growth Factor to improve the heart function
Establishment of novel therapies for pulmonary hypertension
Studying new mechanisms that may be involved in a disease that results in increase in blood pressure in the lungs.
Improving genetic diagnosis in congenital heart disease
Increasing the genetic diagnosis of heart defects will help more families receive an accurate genetic diagnosis, personalised advice concerning the disease in their family and a better estimate of the risk of having a subsequent child with a heart defect
Determining which of three medicines is most likely to have the greatest long term benefit for cardiac patients, and the extent to which each of these medicines are currently used by cardiac patients after discharge from NSW hospitals
Clinical and genetic aspects of hypertrophic cardiomyopathy
Reassessment of risk algorithms in a more homogeneous patient population will allow development of accurate risk prediction scores
Develop new insights into health service of acute chest pain by the application and development of these state-of-the-art investigations to create a paradigm shift in chest pain management and improve healthcare costs
A randomised trial that will examine if catheter ablation is superior to anti-arrhythmic medication in the treatment of ventricular tachycardia in patients with non-ischemic cardiomyopathy
Targeting procoagulant platelets in cardiovascular disease
Investigating the link between procoagulant platelets, platelet mitochondrial function and cardiovascular disease
Live imaging endothelial-immune interactions in atherogenesis
Use see-through zebrafish to literally shed new light on what happens in atherosclerotic plaques using microscopy of the disease inside living zebrafish
Steps towards understanding and preventing early neurological deterioration in ischaemic stroke
Developing and validating a new assay for the detection and prediction of gardiometabolic disease
Develop and validate a blood test that can be widely used, e.g. hospital outpatients, and general practitioner offices, to detect a new molecule in blood
Discovering simple blood test(s) that could detect early onset of chemotherapy-induced cardiotoxicity as well as providing better education and facilitating self-care and empowerment for cancer patients/survivors
Develop CAR T cells to target a broad range of paediatric tumours, and CAR T cells to protect kidney transplants from chronic allograft nephropathy, as well as gene viral vectors to target blinding eye disease and to treat childhood kidney disease
A randomised trial of cell therapy for opportunistic infection after allogeneic stem cell transplant
Test the theory that adding cell therapy to standard antibiotic treatment for infection in patients after bone marrow transplant will improve the immune system leading to better control of serious infections, less serious illness and fewer deaths
Developing a stem cell-based therapy for chronic pain
Developed a long-lasting stem cell therapy that can reverse neuropathic pain
Receptor identification of AAV capsids purposed for gene therapeutic use
Identify genetic variants that may affect receptor expression and enable us to screen patients for those who will be better responders
Uncovering novel mechanosensing pathways that underlie cardiac arrhythmias
Identifying new cellular pathways underlying arrhythmia generation by evaluating how mechanical stress affects the cells that line the chambers of the heart
Online treatment program for postnatal depression and anxiety
Reaching women in underserviced communities in NSW: An online treatment program
Feasibility of an intervention targeting health through exergaming as an alternative to routine treatment
Evaluating an on-line healthy eating and active living support program (Time2BHealthy) for parents of 2-6 year children
Swap what’s packed in the lunchbox
BEEM-HF Randomised Controlled Trial
Improving outcomes following hospitalisation for heart failure in regional and remote NSW
Optimising timing of planned birth to improve newborn outcomes
Are we there yet?: Optimising timing of planned birth to improve newborn outcomes and reduce health service costs
Advance Care Planning in outpatient clinics
Study extension
Online cognitive behavioural therapy for bulimia nervosa
A randomised controlled trial of guided online cognitive behavioural therapy, compared to a waitlist control
Advice while you wait: Empowering families, improving health, reducing waiting times
Development and evaluation of an outreach, family centred model of cardiac rehabilitation for Aboriginal people
Adverse cardiovascular outcome after hypertensive disorders of pregnancy
Altering this trajectory
Management of rural acute coronary syndrome
Defining a new paradigm for assessment and management of acute coronary syndromes (ACS) in rural settings utilising a central clinical decision support service
Implementation of a new model of care for prediabetic patients
Can we prevent progression?
Centralised management system and hot transfer for STEMI
Non-randomised, prospective, controlled trial of a centralised, district-wide STEMI management system implemented by NSW ambulance and all hospitals within the Western NSW Local Health District